Analysis and Determination of Anti-diabetes Drug Acarbose and its Structural Analogs

作者：Wang Ya Jun; Zheng Yu Guo^*; Xue Ya Ping; Wang Yuan Shan; Shen Yin Chu

来源：Current Pharmaceutical Analysis, 2011, 7(1): 12-20.

DOI：10.2174/157341211794708721

• Diabetes
• Acarbose
• Analysis
• Liquid chromatography
• Capillary electrophoresis
• Biosensor

Acarbose is a clinically useful drug for the treatment of type II insulin-independent diabetes as a hypoglycemic agent. This minireview summarized detection and separation methods for the analysis and determination of anti-diabetes drug acarbose and its structural analogs, including HPLC, enzyme-based biosensor and capillary electrophoresis. Besides the protocol, principle behind each technique is presented together with its strengths and weaknesses. Finally, we analyze the future trends in the acarbose analysis.

• 出版日期2011-2
• 单位浙江工业大学