No evidence of increased risk of soft tissue sarcomas in the neighborhood of a steel foundry in Verona

作者：Benedetti Marta^*; Cristini Giovanni; Gallo Stefano; Tessari Roberta; Simonato Lorenzo; Comba Pietro

来源：Annali dell'Istituto Superiore di Sanita, 2010, 46(4): 360-365.

DOI：10.4415/ANN_10_04_03

• sarcoma
• dioxins
• environmental exposure
• epidemiology

The aim of the present study was to evaluate the possible association between occurrence of soft tissue sarcomas in Verona (Italy) and residence near a steel foundry, whose emissions of dioxin-like compounds may be relevant. Exposure to total suspended particulate (TSP) emitted from the plant as estimated by ADMS-urban dispersion model was used as an indirect index of exposure to dioxin-like compounds. Verona municipality was divided in six subareas according to the decreasing levels of estimated TSP exposure, and soft tissue sarcomas cases were mapped according to residence at time of diagnosis. Standardized incidence ratios were computed. No statistically significant departures between observed and expected cases were detected as illustrated by trend-test results.

• 出版日期2010