科研之友
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摘要
Ten new steroidal saponins (1-10) and three known steroidal saponins (11-13) were isolated from a 70% EtOH extract of the roots of Liriope muscari (Decne.) L. H. Bailey. Their structures were determined by analyses of infrared, nuclear magnetic resonance and mass spectroscopic data. These compounds exhibited different levels of cytotoxic activity against MDA-MB-435, 95D, HepG2, HeLa, MCF-7 and A549 cell lines in an in vitro bioassay. The structure-activity relationship of these related compounds was also investigated.
- 出版日期2017
- 单位中国药科大学
