Anthocyanin compositions and biological activities from the red petals of Korean edible rose (Rosa hybrida cv. Noblered)

作者：Lee Jin Hwan; Lee Hyeon Jin; Choung Myoung Gun^*

来源：Food Chemistry, 2011, 129(2): 272-278.

DOI：10.1016/j.foodchem.2011.04.040

• Rosa hybrida
• Petals
• Anthocyanin
• HPLC-DAD-ESI/MS
• Antioxidant
• Anticancer
• Antiallergic

The objectives of the present study were to investigate anthocyanin profiles and their biological properties, including antioxidant, anticancer, and antiallergic, from the red petals of Korean edible rose (Rosa hybrida cv. Noblered). The acidic methanol extract of this species showed potent biological activities at a concentration of 50 mu g/mL. Its anthocyanins were characterised as cyanidin 3,5-di-O-glucoside and pelargonidin 3,5-di-O-glucoside using reversed-phase C(18) column chromatography, NMR spectroscopy, and HPLC-DAD-ESI/MS analysis. Cyanidin 3,5-di-O-glucoside was the predominant constituent (375 mg/100 g), representing about 85% of total content. Cyanidin 3,5-di-O-glucoside exhibited good scavenging activity against DPPH radical with IC(50) value of 55.2 mu g/mL; pelargonidin 3,5-di-O-glucoside showed potent anticancer effects against LNCap (human prostate cell line), ACHN (human renal cell line) and MOLT-4F (human leukaemia cell line) cell cultures, with IC(50) values of 6.43, 18.3, and 6.78 mu g/mL, respectively. Antiallergic activities were only moderate.

• 出版日期2011-11-15