A Highly Selective Fluorescent Probe for Detection of Hydrogen Sulfide in Living Systems: In Vitro and in Vivo Applications

作者:Reja Shahi Imam; Sharma Neetu; Gupta Muskan; Bajaj Payal; Bhalla Vandana; Parihar Ripu D; Ohri Puja; Kaur Gurcharan*; Kumar Manoj*
来源:Chemistry - A European Journal, 2017, 23(41): 9872-9878.
DOI:10.1002/chem.201701124

摘要

A fluorescein-based fluorescent probe has been designed and synthesised that selectively detects H2S in aqueous medium, among various analytes tested. This fluorescein-based fluorescent probe has also been successfully utilised for real-time imaging of exo- and endogenously produced H2S in cancer cells and normal cells. Moreover, the probe can also detect H2S in the rat brain hippocampus at variable depths and in living nematodes.

  • 出版日期2017-7-21