Negative symptoms mediate the influence of theory of mind on functional status in schizophrenia

作者：Mehta Urvakhsh Meherwan^*; Thirthalli Jagadisha; Naveen Kumar Channaveerachari; Kumar J Keshav; Gangadhar Bangalore N

来源：Social Psychiatry and Psychiatric Epidemiology, 2014, 49(7): 1151-1156.

DOI：10.1007/s00127-013-0804-x

• Theory of mind
• Negative symptoms
• Functional disability
• Remission
• Psychosis

We aimed to assess the relationship between social cognition, neurocognition, negative symptoms and functional status in a homogeneous schizophrenia patient group remitted from positive symptoms. Sixty patients underwent assessments of social and neurocognition dimensions recommended by expert panels. A blind rater assessed their functional status. Second order theory of mind (ToM) and negative symptoms had significant correlations with functional status. A bootstrapping analysis used to test for specific mediation models revealed that the effect of second order ToM on functioning was mediated by negative symptoms. Future studies should examine if targeted remediation of ToM improves negative symptoms and thus functioning.

• 出版日期2014-7