DRESS syndrome as a complication of treatment of hepatitis C virus-associated post-inflammatory liver cirrhosis with peginterferon alpha 2a and ribavirin

作者：Janocha Litwin Justyna^*; Pazgan Simon Monika; Simon Krzysztof

来源：Postepy Dermatologii i Alergologii, 2014, 31(6): 401-404.

DOI：10.5114/pdia.2014.40939

• DRESS syndrome
• hepatitis C
• interferon alpha
• ribavirin

Various skin and systemic symptoms may develop as a complication of treatment with different medications and medicinal substances. One of them is a relatively rare drug reaction with eosinophilia and systemic symptoms, referred to as DRESS syndrome. The morphology of skin lesions and the patient's general health can differ; the management involves withdrawal of drugs suspected of triggering DRESS syndrome, and administration of local and systemic glucocorticosteroids. In this paper we present a case of a patient with HCV associated chronic hepatitis, treated with peginterferon alpha 2a (PEG-IFN-alpha 2a) and ribavirin, who developed skin lesions and systemic symptoms typical of DRESS syndrome.

• 出版日期2014