Autoinflammatory diseases and cardiovascular manifestations

作者：Rigante Donato^*; Cantarini Luca; Imazio Massimo; Lucherini Orso Maria; Sacco Emanuela; Galeazzi Mauro; Brizi Maria Giuseppina; Brucato Antonio

来源：Annals of Medicine, 2011, 43(5): 341-346.

DOI：10.3109/07853890.2010.547212

• Autoinflammatory diseases
• cardiovascular abnormalities
• familial Mediterranean fever
• tumour necrosis factor receptor-associated periodic syndrome

A host of clinical scenarios can be depicted in hereditary autoinflammatory diseases, and the cardiovascular system can also be involved especially in familial Mediterranean fever (FMF), caused by mutations in the MEFV gene, and tumour necrosis factor receptor-associated periodic syndrome (TRAPS), caused by mutations in the TNFRSF1A gene. Pericardial diseases are the most represented cardiovascular abnormalities, though the role of MEFV and TNFRSF1A in the initiation of heart involvement has not been demonstrated formally and will be discussed herein.

• 出版日期2011-8