Agrypnia Excitata

作者：Lugaresi Elio; Provini Federica^*; Cortelli Pietro

来源：Sleep Medicine, 2011, 12: S3-S10.

DOI：10.1016/j.sleep.2011.10.004

• Fatal familial insomnia
• Delirium tremens
• Morvan syndrome
• Agrypnia excitata
• Sleep loss
• Thalamus

The concept of Agrypnia excitata (AE) was originally proposed as a concept deriving from the clinical and anatomo-pathological observations obtained in three different diseases, Fatal familial insomnia (FFI), Delirium tremens (DT), and Morvan syndrome (MS). Agrypnia refers to a condition of severely reduced or absent sleep due to organic disorders. Excitata refers to the association of agrypnia with generalized motor and autonomic hyperactivation. AE is a syndrome that has been claimed to relate to a dysfunction in the thalamo-limbic circuits that govern sleep-wake cycles and autonomic activities.

• 出版日期2011-12