Autoimmune hemolytic anemia and giant cell hepatitis: Report of three infants

作者:Unal Sule*; Kuskonmaz Baris; Balamtekin Necati; Baysoy Gokhan; Elmas Selin Aytac; Orhan Diclehan; Kale Gulsev; Yuce Aysel; Gurakan Figen; Gumruk Fatma; Cetin Mualla
来源:Turkish Journal of Hematology, 2010, 27(4): 308-313.
DOI:10.5152/tjh.2010.55

摘要

Giant cell hepatitis associated with direct Coombs' test-positive hemolytic anemia is a rare condition of childhood and the pathogenesis remains unclear. An autoimmune activation and loss of self-tolerance in these patients may be the underlying pathology related to the response of some of the patients to immunosuppressive treatment. Herein, we report the clinical presentation and course of three consecutive patients with this rare condition. We conclude that serum ferritin at diagnosis may be used for prediction of the outcome. (Turk J Hematol 2010; 27: 308-13)

  • 出版日期2010-12