Acromegaly Presenting With Bilateral Vocal Fold Immobility: Case Report and Review of the Literature

作者：Cooper Timothy; Dziegielewski Peter T; Singh Praby; Seemann Robert

来源：Journal of Voice, 2016, 30(6): UNSP 758.e13.

DOI：10.1016/j.jvoice.2015.09.008

• Acromegaly
• Vocal fold fixation
• Vocal fold immobility
• Airway
• Stridor

Objective. To present a case of bilateral vocal fold immobility (BVCI) in a patient with acromegaly and review the current literature describing this presentation.
Design. Case report and literature review.
Setting. Academic tertiary care center.
Methods. English language literature search of online journal databases.
Results. A 56-year-old man presented with 3 months of progressive stridor and shortness of breath. Transnasal flexible endoscopy revealed BVCI. A tracheostomy was performed to secure his airway. Further history was suggestive of acromegaly and imaging demonstrated a pituitary macroadenoma. The diagnosis of acromegaly was made. The patient was treated with octreotide followed by an endoscopic trans sphenoidal resection of the pituitary adenoma. Sixteen months after his initial presentation, a right laser arytenoidectomy was performed and the patient was subsequently decannulated. In the literature to date, 11 cases of BVCI in acromegaly have been reported. These patients often present with stridor and require a tracheostomy. With treatment of their acromegaly, these patients may regain vocal fold mobility and may be decannulated.
Conclusion. Acromegaly with BVCI is a rare presentation. Acute management of the airway of patients with acromegaly presenting with BVCI typically requires a tracheostomy. Aperiod of 15 months should be allowed for restoration of vocal fold mobility before airway opening procedures are considered.

• 出版日期2016-11