At-risk brain tissue identified with arterial spin labeling in neurotuberculosis

作者：Margariti Persefoni^*; Sanchez Montanez Angel; Delgado Ignacio; Elorza Alvarez Izaskun; Vazquez Elida

来源：Pediatric Radiology, 2013, 43(8): 1049-1052.

DOI：10.1007/s00247-013-2624-2

• Neurotuberculosis
• Tuberculous meningitis
• Arteritis
• Arterial spin labeling

A 13-year-old immunocompromised girl developed neurotuberculosis. Arterial spin labeling technique indicated areas of hypoperfusion in the vascular territories of the left posterior cerebral artery and superior cerebellar artery without restricted diffusion, suggesting early tuberculous arteritis. MR angiography confirmed vascular involvement, so adjunctive anticoagulant therapy was initiated. Complete resolution of arterial spin labeling findings was observed 1 month later. This documents early tuberculous vasculopathy revealed by arterial spin labeling in a child with neurotuberculosis. Since there may be a paucity of clinical symptoms in the evolution of arteritis in neurotuberculosis, arterial spin labeling may help indicate early hypoperfusion and alert for modification of treatment before irreversible vascular damage occurs.

• 出版日期2013-8