Anti-Mullerian hormone (AMH) defines, independent of age, low versus good live-birth chances in women with severely diminished ovarian reserve

作者：Gleicher Norbert^*; Weghofer Andrea; Barad David H

来源：Fertility and Sterility, 2010, 94(7): 2824-2827.

DOI：10.1016/j.fertnstert.2010.04.067

• Anti-Mullerian hormone (AMH)
• infertility
• ovarian reserve
• pregnancy
• delivery
• dehydroepiandrosterone (DHEA)

Maximal receiver operating characteristic curve inflections, which differentiate between better and poorer delivery chances in women with diminished ovarian reserve (DOR) independent of age, were at anti-Mullerian hormone (AMH) 1.05 ng/mL (improved odds for live birth 4.6 [2.3-9.1), 95% confidence interval; Wald 18.8, df = 1], although live births occurred even with undetectable AMH. Pregnancy wastage was very low at AMH <= 0.04 ng/mL but significantly increased at AMH 0.41-1.05 ng/mL, resulting in similarly low live-birth rates at all AMH levels <= 1.05 ng/mL and significantly improved live-birth rates at AMH >= 1.06 ng/mL. (Fertil Steril (R) 2010;94:2824-7.

• 出版日期2010-12