Disintegration properties of blank tablets containing carboxymethyl-cellulose calcium prepared by slurry process

作者:Liang, Dong; Deng, Yong-Hong; Tong, Zhen; Liu, Xin-Xing; Zeng, Fang; Liu, Ping; Pan, Yu-Fang
来源:Journal of South China University of Technology(Natural Science Edition), 2001, 29(12): 34-37.

摘要

Carboxymethylcellulose calcium for pharmaceutical necessities is prepared by slurry process. Compared with other disintegration agents, the present Ca-CMC has quicker disintegration rate. No calcifying agents remain in the present Ca-CMC samples by slurry process and the content of other impurities satisfies the requirement of pharmaceutical necessities. In addition, the reason that Ca2+ cannot replace Na+ completely in preparing process is discussed.

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