Attenuation of Cardiovascular Responses and Upper Airway Events to Tracheal Extubation by Low Dose Propofol

作者：Vaziri Mohammad Taghy Moein; Jouybar Reza^*; Vaziri Nader Moein; Vaziri Najmeh Moein; Panah Ashkan

来源：Iranian Red Crescent Medical Journal, 2013, 15(4): 298-301.

DOI：10.5812/ircmj.1846

• Propofol
• Hemodynamics
• Respiratory System
• Airway Extubation

Background: Hemodynamic changes and respiratory tract complications are often followed by tracheal extubation. These events may be dangerous in neurosurgical patients and those with cardiovascular disease or at an old age. %26lt;br%26gt;Objectives: The aim of this study is to investigate the attenuation of cardiovascular responses and upper airway events resulting from tracheal extubation by low dose propofol. %26lt;br%26gt;Materials and Methods: 80 patients with ASA physical status I, undergoing an elective surgery in a double blind manner received 0.5mg/kg propofol or normal saline 2 minutes before extubation. Heart rate and blood pressure and quality of tracheal extubation were recorded. %26lt;br%26gt;Results: Heart rate and blood pressure in patients receiving propofol were less than the control group (P %26lt; 0.05) at the time of injection of propofol, but there were no differences between the two groups at the time of extubation. %26lt;br%26gt;Conclusions: We concluded that propofol can reduce SBP, DBP, MAP, HR %26 cough production at the time of injection but there were no significant changes in these parameters after extubation.

• 出版日期2013-4