Are women who have had a preterm twin delivery at greater risk of preterm birth in a subsequent singleton pregnancy?

作者：Facco Francesca L^*; Nash Kate; Grobman William A

来源：American Journal of Obstetrics and Gynecology, 2007, 197(3): 253.e1.

DOI：10.1016/j.ajog.2007.06.049

• premature
• preterm birth
• twin gestation

OBJECTIVE: The purpose of this study was to determine whether preterm birth of twins is associated with an increased risk of preterm birth in a subsequent singleton pregnancy.
STUDY DESIGN: All patients who delivered a twin gestation and a subsequent singleton pregnancy at Northwestern Memorial Hospital during a 10-year period were identified. We used a cohort study design, comparing the outcomes of the singleton pregnancies in women with preterm twin deliveries to those pregnancies with term twin deliveries.
RESULTS: One hundred sixty-seven women delivered twins followed by a singleton pregnancy. Women whose twin delivery was preterm (n = 99) were more likely than those who had delivered a term twin pregnancy ( n = 68) to deliver a subsequent preterm singleton pregnancy (13.1% vs 2.9%; odds ratio, 5.0; 95% CI, 1.1, 22.9).
CONCLUSION: Preterm birth of twins is associated with an increased risk of preterm delivery in a subsequent singleton pregnancy.

• 出版日期2007-9
• 单位西北大学