Asymmetric Organocatalytic Wittig [2,3]-Rearrangement of Oxindoles

作者：Oseka Maksim; Kimm Mariliis; Kaabel Sandra; Jarving Ivar; Rissanen Kari; Kanger Tonis^*

来源：Organic Letters, 2016, 18(6): 1358-1361.

DOI：10.1021/acs.orglett.6b00291

A highly enantioselective organocatalytic [2,3]-rearrangement of oxindole derivatives is presented. The reaction was catalyzed by squaramide, and this provides access to 3-hydroxy 3-substituted oxindoles in high enantiomeric purities.

• 出版日期2016-3-18