Artificial facial nerve reflex restores eyelid closure following orbicularis oculi muscle denervation

作者：Wang, Yujuan; Li, Keyong^*; Liu, Jingquan; Xu, Dongyue; Rui, Yuefeng; Yang, Chunsheng

来源：Neural Regeneration Research, 2010, 5(22): 1750-1755.

DOI：10.3969/j.issn.1673-5374.2010.22.012

• artificial facial nerve reflex
• facial paralysis/therapy
• electrical stimulation
• electromyography
• nerve regeneration

To date, treatment of peripheral facial paralysis has focused on preservation of facial nerve integrity. However, with seriously damaged facial nerve cases, it is difficult to recover anatomical and functional integrity using present therapies. Therefore, the present study utilized artificial facial nerve reflex to obtain orbicularis oculi muscle (OOM) electromyography signals on the uninjured side through the use of implanted recording electrodes. The implanted electrical chips analyzed facial muscle motion on the uninjured side and triggered an electrical stimulator to emit current pulses, which resulted in stimulation of injured OOM contraction and maintained bilateral symmetry and consistency. Following signal recognition, extraction, and computer analysis, electromyography signals in the uninjured OOM resulted in complete eyelid closure, which was consistent with the voltage threshold for eye closure. These findings suggested that artificial facial nerve reflex through the use of implanted microelectronics in unilateral peripheral facial paralysis could restore eyelid closure following orbicularis oculi muscle denervation.

• 出版日期2010-11-30
• 单位上海交通大学