摘要

This is an overall review about the development of synthesis and applications of chiral crown ether compounds. Firstly, chiral crown ether compounds are classified according to the source of their chiral centers. The synthetic methods are then introduced respectively. Finally, three major applications of chiral crown ether are reported: i. e. (1) Chiral recognition and resolution of enantiomer, (2) Asymmetric catalytic effect, (3) Selective complexation and extraction of ion.