科研之友
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摘要
Background: The aim of this study was to compare the diagnostic accuracy of 64-slice multidetector computed tomography (MDCT) with conventional coronary angiography to detect graft patency and stenosis. %26lt;br%26gt;Methods: In this retrospective analysis, we included a total of 284 subjects (210 men, 73.9%; mean +/- SD age, 62.6 +/- 9.9) and evaluated 684 bypass grafts using a dual-source 64-slice MDCT scanner The mean +/- SD time interval between coronary artery bypass grafting operation and MDCT was 30.8 +/- 6.2 months. The mean +/- SD interval between MDCT angiography and conventional coronary angiography was 14.2 +/- 3.6 days. Significant stenosis was defined as lesions causing 50% or greater luminal narrowing. All atherosclerotic lesion components were assessed on per-segment basis. %26lt;br%26gt;Results: All of the 684 grafts (420 venous and 264 arterial grafts) were evaluable and included in the analysis. For the detection of 50% or greater graft stenosis, the sensitivity, specificity, positive predictive value and negative predictive value of MDCT was 98.3%, 99.3%, 98.3%, and 99.3% for venous grafts and 100%, 99.5%, 98.0%, and 100% for arterial grafts. In detection of graft patency, the sensitivity, specificity, positive predictive value, and negative predictive value of MDCT was 99.6%, 97.2%, 99.0%, and 99.0% for venous grafts and 99.5%, 97.5%, 99.5%, and 97.5% for arterial grafts. Diagnostic accuracy for the detection of graft patency was 99% (416/420) and 99.2% (262/264) for venous and arterial grafts, respectively. %26lt;br%26gt;Conclusion: The diagnostic accuracy of dual-source 64-slice MDCT angiography for evaluating coronary artery bypass grafts patency and stenosis was high. Dual-source 64-slice MDCT can be used for the evaluation of patients after coronary artery bypass grafting.
- 出版日期2012-12
