Highly sensitive non-enzymatic glucose sensor based on over-oxidized polypyrrole nanowires modified with Ni(OH)(2) nanoflakes

作者：Yang Jiao; Cho Misuk; Pang Changhyun; Lee Youngkwan^*

来源：Sensors and Actuators B: Chemical , 2015, 211: 93-101.

DOI：10.1016/j.snb.2015.01.045

• Over oxidized polypyrrole
• Ni(OH)(2) nanoflake
• Biosensor
• Non enzymatic
• Glucose

The electrocatalytic activity of over-oxidized polypyrrole nanowires electrode modified with nickel hydroxide nanoflakes (nf-Ni(OH)(2)@oPPyNW) was investigated for its application to an amperometric glucose sensor. The oPPyNW were electrodeposited on graphite electrode by chronoamperometry, and then, Ni(OH)(2) nanoflakes were grown on the oPPyNW by chemical bath method. The surface morphology of the nf-Ni(OH)(2)@oPPyNW-modified electrode was characterized by scanning electron microscopy, and its composition was verified by X-ray photoelectron spectroscopy. Following the exploration of optimum deposition conditions, chronoamperometry was used to determine the varying concentrations of glucose in an alkaline solution. The as-prepared nf-Ni(OH)(2)@oPPyNW electrode demonstrated excellent performance in terms of electrocatalytic activity, response rate, and stability. It was capable of detecting glucose in a wide dynamic detection range of 0.001-4.863 mM and was able to selectively detect glucose in the presence of several electroactive species such as ascorbic acid, dopamine, L-aspartic acid, and uric acid. At the same time, the proposed electrode exhibited a high sensitivity of 1049.2 mu AmM-1 cm(-2) with a low detection limit of 0.3 mu M, illustrating it as a tool in a potential strategy to develop a fast, sensitive, selective, and stable electrochemical sensor for early diabetes diagnosis.

• 出版日期2015-5