Decreased desychronisation during self-paced movements in frequency bands involving sensorimotor integration and motor functioning in Parkinson's disease

作者：Lim Vanessa K^*; Hamm Jeff P; Byblow Winston D; Kirk Ian J

来源：Brain Research Bulletin, 2006, 71(1-3): 245-251.

DOI：10.1016/j.brainresbull.2006.09.009

• Parkinson's disease
• movement tasks
• oscillations
• alpha
• beta
• sensorimotor integration
• ERD
• SMA

This study examined sensorimotor integration and motor functioning in seven patients with Parkinson's disease (PD) who had mild symptoms, and seven age-matched controls. Neuro-oscillations were recorded by high-density 128-channel electroencephalography (EEG). Participants were required to perform two tasks: simple tapping of the index finger and thumb and a complex Luria finger apposition task. Both tasks were performed unimanually and bimanually. There were no significant group differences in the task-related power (TRPow) within alpha 1 (mu1) or in beta 1 frequencies (beta 1). In contrast, there were significant group differences in the alpha 2 (mu2) and beta 2 frequencies (beta 2). Patients had less desychronisation than controls at the electrodes covering the central regions of the scalp. Alpha 2 and beta 2 frequencies have been associated with task-specific sensorimotor integration and motor function, respectively. This activity difference in patients with Parkinson's disease may be due to deficits in sensorimotor integration.

• 出版日期2006-12-11