Novel acridine-based thiosemicarbazones as 'turn-on' chemosensors for selective recognition of fluoride anion: a spectroscopic and theoretical study

作者：Isaac Ibanga Okon; Munir Lqra; ai Rashida Mariya; Ali Syed Abid; Shafiq Zahid; Islam Muhammad; Ludwig Ralf; Ayub Khurshid^*; Khan Khalid Mohammed; Hameed Abdul^*

来源：Royal Society Open Science, 2018, 5(7): 180646.

DOI：10.1098/rsos.180646;180646

• acridine
• thiosemicarbazldes
• fluoride (F-)
• UV absorption
• fluorescence
• density functional theory calculations

New thiosemicarbazide-linked acridine 3a-c were prepared and investigated as chemosensors for the detection of biologically and environmentally important anions. The compounds 3a-c were found selective for fluoride (F-) with no affinity for other anions, i.e. -OAc, Br-, I-,HSO4-, SO42-, PO4 circle-, ClO3-, CIO4-, CN- and SCN-. Further, upon the gradual addition of a fluoride anion (F-) source (tetrabutylammonium fluoride), a well-defined change in colour of the solution of probes 3a-c was observed. The anion-sensing process was studied in detail via UV-visible absorption, fluorescence and H-1-NMR experiments. Moreover, during the synthesis of acridine probes 3a-c nickel fluoride (NiF2), a rarely explored transition metal fluoride salt, was used as the catalyst. Theoretical studies via density functional theory were also carried out to further investigate the sensing and anion (F-) selectivity pattern of these probes.

• 出版日期2018-7