Disseminated typical bronchial carcinoid tumor

作者：Novkovic Dobrivoje^*; Skuletic Vesna; Vukovic Jelena; Cerovic Snezana; Tomic Ilija; Karlicic Vukojica; Stojisavljevic Marko

来源：Vojnosanitetski Pregled, 2013, 70(5): 516-521.

DOI：10.2298/VSP1305516N

• carcinoid tumor
• lung neoplasms
• diagnosis
• neoplasm metastasis
• liver
• skeleton
• diagnosis, differential
• immunohistochemistry

Introduction. Bronchial cardnoids belong to a rare type of lung tumors. If they do not expose outstanding neuroendocrine activity, they develop without clearly visible symptoms. They are often detected during a routine examination. According to their clinical pathological features, they are divided into typical and atypical tumors. Typical bronchial carcinoids metastasize to distant organs very rarely. Localized forms are effectively treated by surgery. The methods of conservative treatment should be applied in other cases. Case report. We presented a 65-year-old patient with carcinoid lung tumor detected by a routine examination. Additional analysis (chest X-ray, computed tomography of the chest, ultrasound of the abdomen, skeletal scintigraphy, bronhoscopy, histopathological analysis of the bioptate of bronchial tumor, as well as bronchial brushing cytology and immunohistochemical staining performed with markers specific for neuroendocrine tumor) proved a morphologically typical lung carcinoid with dissemination to the liver and skeletal system, which is very rarely found in typical carcinoids. Conclusion. The presented case with carcinoid used to be showed morphological and pathohistological characteristics of typical bronchial carcinoid. With its metastasis to the liver and skeletal system it demonstrated unusual clinical course that used to be considered as rare phenomenon. Due to its frequent asymptomatic course and varied manifestation, bronchial carcinoid could be considered as a diagnostic challenge requiring a multidisciplinary approach.

• 出版日期2013-5
• 单位中国人民解放军军事医学科学院