Differences between the macroscopic and tracer level chemistry of rhenium and technetium: contrasting cage isomerisation behaviour of Re(I) and Tc(I) carborane complexes

作者：Armstrong Andrea F; Valliant John F^*

来源：Dalton Transactions, 2010, 39(35): 8128-8131.

DOI：10.1039/c0dt00490a

Carboranes form stable complexes with the [M(CO)(3)](+) (M = (99m)Tc, Re) core and are viable ligands for the development of targeted radiopharmaceuticals. (99m)Tc- carborane complexes were found to exhibit substantially different 1,2 -> 1,7 cage isomerisation behaviour than their Re counterparts, challenging the validity of the routine use of rhenium as a surrogate for the development of technetium- 99m basedmolecular imaging agents.

• 出版日期2010