Adenine Molecularly Imprinted Polymer-Coated Submicrometer Silica Gel Particles

作者:Wybranska Katarzyna; Niemiec Wiktor; Szczubialka Krzysztof; Nowakowska Maria*; Morishima Yotaro
来源:Chemistry of Materials, 2010, 22(18): 5392-5399.
DOI:10.1021/cm100845u

摘要

Adenine molecularly imprinted material was obtained. Well-defined silica gel particles of submicrometer size were coated with ultrathin polymeric layers, first with a polycationic poly(allylamine hydrochloride) layer that acted as a binder for the second outer layer of a photo-crosslinkable thymine-containing polyanion. Adenine template was adsorbed by the complementary thymine chromophores attached to the polymer and its imprints were created by photo-cross-linking of the outer polymer layer. The imprinted particles have shown the ability to recognize adenine and adenosine, an adenine-based nucleoside, whereas no imprinting effect was observed for purine.

  • 出版日期2010-9-28