Morphological and Functional Assessment of Carotid Plaques Have Similar Predictive Accuracy for Coronary Artery Disease

作者：Toutouzas Konstantinos^*; Benetos Georgios; Drakopoulou Maria; Michelongona Archontoula; Nikolaou Charalampia; Masoura Constantina; Stathogiannis Konstantinos; Aggeli Constantina; Tsiamis Eleftherios; Siores Elias; Stefanadis Christodoulos

来源：Stroke, 2013, 44(9): 2607-2609.

DOI：10.1161/STROKEAHA.113.002462

• carotid arteries
• coronary artery disease
• inflammation
• microwaves

Background and Purpose Microwave radiometry allows noninvasive in vivo measuring of internal temperature of tissues reflecting inflammation. In the present study, we evaluated the predictive accuracy of this method for the diagnosis of coronary artery disease (CAD).
Methods Consecutive patients (n=287) scheduled for coronary angiography were included in the study. In carotid arteries of both groups, the following measurements were performed: (1) intima-media thickness (IMTmax) and (2) temperature measurements by microwave radiometry (T-max). C-statistic and net reclassification improvement were used to compare the prediction ability of the markers IMTmax and T-max for the presence of CAD and multivessel CAD.
Results Of 287 patients, 239 had stenoses 50% (CAD group), and 48 did not have significant stenoses (NO-CAD group). T-max was an independent predictor for the presence of CAD and multivessel CAD, showing similar predictive accuracy to intima-media thickness, as assessed by c-statistic and net reclassification improvement.
Conclusions Local inflammatory activation, as detected by microwave radiometry, has similar predictive accuracy to intima-media thickness for the presence and extent of CAD.

• 出版日期2013-9