Advancements in brachytherapy

作者：Tanderup Kari^*; Menard Cynthia; Polgar Csaba; Lindegaard Jacob Christian; Kirisits Christian; Poetter Richard

来源：Advanced Drug Delivery Reviews, 2017, 109: 15-25.

DOI：10.1016/j.addr.2016.09.002

• Brachytherapy
• Radiotherapy
• Image guided therapy
• Hypofractionation
• Focal therapy
• Technology
• Imaging

Brachytherapy is a radiotherapy modality associated with a highly focal dose distribution. Brachytherapy treats the cancer tissue from the inside, and the radiation does not travel through healthy tissue to reach the target as with external beam radiotherapy techniques. The nature of brachytherapy makes it attractive for boosting limited size target volumes to very high doses while sparing normal tissues. Significant developments over the last decades have increased the use of 3D image guided procedures with the utilization of CT, MRI, US and PET. This has taken brachytherapy to a new level in terms of controlling dose and demonstrating excellent clinical outcome. Interests in focal, hypofractionated and adaptive treatments are increasing, and brachytherapy has significant potential to develop further in these directions with current and new treatment indications.

• 出版日期2017-1-15