Availability of 24-h urine collection method on dietary phosphorus intake estimation

作者：Sakuma Masae^*; Morimoto Yuuka; Suzuki Yukie; Suzuki Akitsu; Noda Saaya; Nishino Kanaho; Ando Sakiko; Ishikawa Makoto; Arai Hidekazu

来源：Journal of Clinical Biochemistry and Nutrition, 2017, 60(2): 125-129.

DOI：10.3164/jcbn.16-50

• dietary phosphorus
• 24-h urine collection
• urine phosphorus excretion
• urine nitrogen excretion
• loading test

Accurate assessment of dietary phosphorus intake is necessary to prevent hyperphosphatemia. The aim of this study was to evaluate the 24-h urine collection method for estimation of phosphate intake in healthy males. Two experiments, a 1-day and a 5-day loading test, were performed. After an overnight fast, subjects consumed test meals, 24-h urine collection was performed, and blood samples were obtained. In the 5-day loading test, a phosphorus supplement was orally administered on day 3. The association between the phosphorus content of test meals and urinary excretion, anthropometric indices, and blood biomarkers was analyzed to develop a more precise formula for estimating phosphorus intake. In the 1 day loading test, the standard deviation of predictive phosphorus intake, based on multiple linear regression analysis, was less than that for the phosphorus absorption rate. In the 5-day loading test, urinary phosphorus excretion was similar on days 2, 4 and 5, but was significantly higher on day 3 after phosphorus supplementation. Our results indicate that estimation of dietary phosphorus intake with the 24-h urine collection method, using the amount of phosphorus and urea nitrogen excretion, may increase the precision of short-term monitoring.

• 出版日期2017-3-1