Neem cake as a promising larvicide and adulticide against the rural malaria vector Anopheles culicifacies (Diptera: Culicidae): a HPTLC fingerprinting approach

作者：Benelli Giovanni; Chandramohan Balamurugan; Murugan Kadarkarai; Madhiyazhagan Pari; Kovendan Kalimuthu; Panneerselvam Chel****my; Dinesh Devakumar; Govindarajan Marimuthu; Higuchi Akon; Toniolo Chiara; C****e Angelo; Nicoletti Marcello

来源：Natural Product Research, 2017, 31(10): 1185-1190.

DOI：10.1080/14786419.2016.1222390

• Anopheline
• arbovirus
• eco-friendly insecticides
• mosquito vectors
• ovicidal activity

Mosquitoes are insects of huge public health importance, since they act as vectors for important pathogens and parasites. Here, we focused on the possibility of using the neem cake in the fight against mosquito vectors. The neem cake chemical composition significantly changes among producers, as evidenced by our HPTLC (High performance thin layer chromatography) analyses of different marketed products. Neem cake extracts were tested to evaluate the ovicidal, larvicidal and adulticidal activity against the rural malaria vector Anopheles culicifacies. Ovicidal activity of both types of extracts was statistically significant, and 150ppm completely inhibited egg hatching. LC50 values were extremely low against fourth instar larvae, ranging from 1.321 (NM1) to 1.818ppm (NA2). Adulticidal activity was also high, with LC50 ranging from 3.015 (NM1) to 3.637ppm (NM2). This study pointed out the utility of neem cake as a source of eco-friendly mosquitocides in Anopheline vector control programmes.

• 出版日期2017
• 单位中央民族大学