Dietary conjugated linoleic acid and long-chain n-3 fatty acids in mammary and prostate cancer protection: a review

作者：Heinze Veronica M^*; Actis Adriana B

来源：International Journal of Food Sciences and Nutrition, 2012, 63(1): 66-78.

DOI：10.3109/09637486.2011.598849

• n-6 and n-3 fatty acids
• conjugated linoleic acid
• eicosapentaenoic acid
• docosahexaenoic acid
• breast cancer

The role of dietary fatty acids on cancer is still controversial. To examine the current literature on the protective role of conjugated linoleic acid (CLA) and marine long-chain fatty acids [eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)] and the risk of breast and prostate cancer, data from 41 case-control and cohort studies and relevant in vitro and animal experiments were included in this 2000-2010 revision. Epidemiological studies on CLA intake or its tissue concentration related to breast and prostate tumorigenesis are not conclusive; EPA and DHA intake have shown important inverse associations just in some studies. Additional research on the analysed association is required.

• 出版日期2012-2