Hemifacial spasm, vertebrobasilar dolichoectasia and neurofibromatosis type 1

作者：de Pablo Fernandez E^*; Correas Callero E; Sierra Hidalgo F; Posada I J

来源：Journal of Clinical Neuroscience, 2012, 19(7): 1046-1047.

DOI：10.1016/j.jocn.2011.05.033

• Hemifacial spasm
• Neurofibromatosis
• Vasculopathy
• Vertebrobasilar dolichoectasia

Hemifacial spasm (HFS) is usually produced by compression of the facial nerve by tortuous blood vessels at the root exit zone, including vertebrobasilar dolichoectasia (VBD). Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder with a variety of symptoms, affecting mainly the skin and nervous system. Cerebrovascular abnormalities are becoming a recognized complication of the disease and the most constantly described lesions are stenosis and occlusions affecting the internal carotid artery. VBD has rarely been associated with NF1. We report a 38-year-old female patient with HFS produced by VBD with NF1 presenting with other cerebrovascular abnormalities associated with this disease. We discuss the possible association between these three entities, assuming that a causal relationship may be established and that VBD is part of the spectrum of vascular abnormalities caused by NF1 in this patient.

• 出版日期2012-7