摘要
The multicomponent reactions of 1,3-thiazolidinedione, malononitrile, aromatic aldehydes and alpha-phenylethylamine or beta-phenylethylamine in acetonitrile at room temperature produce dihydrothiophene ureidoformamide derivatives in moderate yields through a domino ring-opening/recyclization reaction of 1,3-thiazolidinedione. On treatment with DDQ, dihydrothiophenes are dehydrogenated to convert efficiently to thiophenes in the mild condition.
- 出版日期2010-4
- 单位扬州大学