Molecular characterization of new described kobuvirus in dogs with diarrhea in China

作者：Kong, Ning; Zuo, Yewen; Wang, Zhongze; Yu, Hai; Zhou, En-min; Shan, Tongling^*; Tong, Guangzhi^*

来源：SpringerPlus, 2016, 5(1): 2047.

DOI：10.1186/s40064-016-3738-4

• Molecular characterization
• Canine kobuvirus
• Phylogenetic analysis

Canine kobuvirus (CaKVs) was a newly described virus detected in dogs in the US and Italy. To learn more about CaKVs, 5 of 106 fecal samples from diarrhea dogs were positive with CaKVs in China, and the full genome of CaKVs strain CH-1 isolated from dog with diarrhea was sequenced. The genome consists of 8186 nucleotides, excluding the 3' poly (A) tail, and an open reading frame that maps between nucleotide positions 601 and 7943 which encodes a 2446 amino acid polyprotein. Based on the complete amino acid sequence of polyprotein, phylogenetic analysis showed that CH-1 was grouped along with other canine kobuvirus strains detected in the USA (US-PC0082, AN211D).

• 出版日期2016-11-30
• 单位西北农林科技大学; 中国农业科学院上海兽医研究所