Disability in women suffering from interstitial cystitis/bladder pain syndrome

作者：Katz Laura^*; Tripp Dean A; Nickel J Curtis; Mayer Robert; Reimann Maria; van Ophoven Arndt

来源：BJU International, 2013, 111(1): 114-121.

DOI：10.1111/j.1464-410X.2012.11238.x

• disability
• interstitial cystitis/bladder pain syndrome
• negative affect
• pain catastrophizing

Objectives %26lt;br%26gt;To examine a biopsychosocial framework of patient disability in patients suffering from interstitial cystitis/bladder pain syndrome (IC/BPS). %26lt;br%26gt;To evaluate the impact of psychosocial factors on the relationship between pain and disability within women with IC/BPS. %26lt;br%26gt;Patients and Methods %26lt;br%26gt;Women with IC/BPS completed questionnaires including demographics, symptoms and problems (IC Symptom and Problem Indices), pain (McGill Pain Questionnaire), quality of life (Medical Outcomes Study - Short Form 12), disability (Pain Disability Index) and psychosocial variables (Center for Epidemiological Studies - Depression Scale; State Trait Anxiety Inventory; Pain Catastrophizing Scale; Multidimensional Scale of Perceived Social Support). %26lt;br%26gt;Exploratory and confirmatory factor analyses were employed to determine the factor structure and composition of the measured variables. %26lt;br%26gt;Structural equation modelling was used to examine model fit and the mediation effect of the psychosocial factors (negative affect, catastrophizing and social support) on impairments and functional disability. %26lt;br%26gt;Results %26lt;br%26gt;Questionnaires completed by 196 women with IC/BPS provided data for the present study. %26lt;br%26gt;The measurement model showed good fit to the data. %26lt;br%26gt;Negative affect (P %26lt; 0.001) and catastrophizing (P %26lt; 0.001) were significant in explaining the relationship between impairments and functional disability, whereas social support did not. %26lt;br%26gt;Conclusions %26lt;br%26gt;Disability in patients suffering from IC/BPS is partially explained by the impact of negative affect and catastrophizing. %26lt;br%26gt;As a result of the refractory nature of IC/BPS, patient management within a biopsychosocial framework represents an essential area of investigation. %26lt;br%26gt;Decreases in negative affect and catastrophizing will probably lead to improvements in pain-related disability.

• 出版日期2013-1