NbCl5 as an Efficient Catalyst for Chemoselective Synthesis of 1,1-Diacetates Under Solvent-Free Conditions

作者：Gao Shu Tao; Zhao Ying; Li Chao; Ma Jing Jun; Wang Chun^*

来源：Synthetic Communications, 2009, 39(12): 2221-2229.

DOI：10.1080/00397910802654674

• Aldehydes
• 1
• 1-diacetates
• NbCl5
• solvent-free conditions

A mild and efficient method for the chemoselective preparation of 1,1-diacetates catalyzed by NbCl5(5mmol%) under solvent-free conditions has been developed. The yields are in the range of 93-98%. This protocol offered several advantages, including low catalyst loading, good yields, short reaction times, and environmentally friendliness.

• 出版日期2009
• 单位河北农业大学