A Convenient One-Step Synthesis of Stable beta-Amino Alcohol N-Boranes from alpha-Amino Acids

作者:Pinaka Afroditi; Vougioukalakis Georgios C*; Dimotikali Dimitra; Psyharis Vassilis; Papadopoulos Kyriakos
来源:Synthesis, 2012, 44(7): 1057-1062.
DOI:10.1055/s-0031-1289727

摘要

Novel, non-cyclic beta-amino alcohol N-boranes are isolated from the sodium borohydride-sulfuric acid assisted direct reduction of a series of alpha-amino acids. The reduction takes place in one step under mild conditions and affords the products in good yields.

  • 出版日期2012-4