AMBULATORY BLOOD PRESSURE PATTERNS IN PATIENTS WITH RETINAL VEIN OCCLUSION

作者：Rao Vishal N; Ulrich J Niklas; Viera Anthony J; Parlin Anna; Fekrat Sharon; Chavala Sai H^*

来源：Retina-The Journal of Retinal and Vitreous Diseases, 2016, 36(12): 2304-2310.

DOI：10.1097/IAE.0000000000001071

• retinal vein occlusion
• ambulatory blood pressure monitoring
• nondipper
• cardiovascular disease risk
• epidemiology
• diagnostic tests

Purpose: Failure of blood pressure BP) to dip during sleep nondipper pattern) is associated with cardiovascular disease and stroke. The prevalence and degree of nondipping and masked hypertension in patients with retinal vein occlusion RVO), which is associated with stroke, has not been previously examined.
Methods: We measured clinic and 24-hour ambulatory BPs in 22 patients with RVO and 20 control participants without known eye disease matched by age and sex. Mean BP dipping, defined as the ratio of difference in mean awake and sleep systolic BPs to mean awake systolic BP, and masked and nocturnal hypertension were compared between groups.
Results: Mean 24-hour ambulatory BP was 144/79 mmHg among those with RVO and 136/77 mmHg among controls. Patients with RVO had an almost 2-fold higher prevalence of nondipping pattern 80.8% [95% confidence interval, 52.8-94.1] vs. 50.4% [95% confidence interval, 26.1-74.5]; P = 0.008). Average sleep systolic BP dip in patients with RVO was 6.1% versus 11.9% in controls P = 0.004). More patients with RVO had masked hypertension by ambulatory BPs than controls 71% vs. 50%), but this difference was not statistically significant.
Conclusion: Our data suggest an association between RVO and nondipper BP pattern. Ambulatory BP monitoring may be useful in the evaluation of patients with RVO by identifying those who may benefit from more aggressive BP control.

• 出版日期2016-12