A Synthetic Method for Palladium-Catalyzed Stannylation at the 5-and 6-Benzo Positions of Indoles

作者：Corcoran Emily B; Williams Anna B; Hanson Robert N^*

来源：Organic Letters, 2012, 14(17): 4630-4633.

DOI：10.1021/ol302076d

The stannylation of indole derivatives proceeds in good yields under palladium catalysis (5 mol %) without protection of the indolic nitrogen. The general utility of both PdCl2(PhCN)(2)/PCy3 and Pd(2)dba(3)/PCy3 as catalytic systems for the stannylation of three indole derivatives, with varying degrees of electron density, is presented.

• 出版日期2012-9-7
• 单位东北大学