Alzheimer's disease Relationship between cognitive aspects and power and coherence EEG measures

作者：Fonseca Lineu C^*; Tedrus Gloria M A S; Prandi Larissa R; Almeida Adriana M; Furlanetto Danilo S

来源：Arquivos de Neuro-Psiquiatria, 2011, 69(6): 875-881.

DOI：10.1590/s0004-282x2011000700005

• dementia
• cognition
• Alzheimer's disease
• electroencephalography

Objective: To evaluate the relationship between specific cognitive aspects and quantitative EEG measures, in patients with mild or moderate Alzheimer's disease (AD). Method: Thirty-eight AD patients and 31 controls were assessed by CERAD neuropsychological battery (Consortium to Establish a Registry for AD) and the electroencephalogram (EEG). The absolute power and coherences EEG measures were calculated at rest. The correlations between the cognitive variables and the EEG were evaluated. Results: In the AD group there were significant correlations between different coherence EEG measures and Mini-Mental State Examination, verbal fluency, modified Boston naming, word list memory with repetition, word list recall and recognition, and constructional praxis (p<0.01). These correlations were all negative for the delta and theta bands and positive for alpha and beta. There were no correlations between cognitive aspects and absolute EEG power. Conclusion: The coherence EEG measures reflect different forms in the relationship between regions related to various cognitive dysfunctions.

• 出版日期2011-12