科研之友
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摘要
The aim of this study was to determine the timecourse of recovery of immunoendocrine responses following prolonged cycling. With the approval of the Ethics Committee, ten healthy men ( age 21.6 +/- 0.9 years, height 1.77 +/- 0.01 m, body mass 66.9 +/- 1.8 kg, VO(2)max 54.2 +/- 2.0 ml kg(-1) min(-1); means +/- SEM) performed either a 2 h cycling trial at 55% peak aerobic power or a resting control trial in a counterbalanced order, separated by at least 6 days. No food was consumed, though water ingestion was allowed ad libitum, until trials were completed. Venous blood samples were collected at pre-exercise, post-exercise, and at 1, 3, 6 and 9 h post-exercise. Haematological analysis was performed using an automated cell counter. Plasma concentrations of hormones were determined using ELISA kits. Neutrophil degranulation (bacteria-stimulated) and oxidative burst (formyl-methionyl-leucyl-phenylalanine-induced) were measured using an ELISA kit and a chemiluminescence assay, respectively. Results were analyzed using two-factor repeated measures ANOVA with post hoc Tukey tests and paired t tests applied where appropriate. The main findings of this study were that, compared with the resting trial, an acute single bout of prolonged exercise ( 1) decreased plasma glucose concentrations but increased circulating leukocyte, neutrophil, and monocyte counts for 9 h; ( 2) increased plasma cortisol concentrations but suppressed neutrophil function on a per cell basis for 6 h. In conclusion, the findings of this study suggest that the impact of a single bout of prolonged cycling on immunoendocrine responses would be recovered around 9 h post-exercise at fasted status.
- 出版日期2007-11
- 单位东华大学
