DDT Exposure, Work in Agriculture, and Time to Pregnancy Among Farmworkers in California

作者：Harley Kim G^*; Marks Amy R; Bradman Asa; Barr Dana B; Eskenazi Brenda

来源：Journal of Occupational and Environmental Medicine, 2008, 50(12): 1335-1342.

DOI：10.1097/JOM.0b013e31818f684d

Objective: This study examined whether exposure to pesticides, including dichlorodiphenyltrichloroethane (DDT), was associated with longer time to pregnancy (TTP). Methods: Pregnant women (N = 402) living in a migrant farmworker community were asked how many months the), took to conceive. Women reported their and their partners' occupational and home pesticide exposure preceding conception. In a subset (N = 289), levels of DDT and dichlorodiphenyldichloroethylene (DDE), were measured in maternal serum. Results: No associations were seen with 13, p'-DDT, o, p'-DDT, or p, p'-DDE. Maternal occupational pesticide exposure (fecundability odds ratios [fOR] = 0.8, 95% CI: 0.6 to 1.0), home pesticide use (fOR = 0.6, 95% and residence within 200 ft of an agricultural field (fOR = 0.7, 95% CI: 0.4 to 0.9), CI: 0.5 to 1.0) were associated with reduced fecundability (ie, longer TTP). Conclusions: Longer TTP was seen among women, but not men, reporting exposure to agricultural and home pesticides. (J Occup Environ Med. 2008;50:1335-1342)

• 出版日期2008-12