A ruthenium-catalyzed coupling of alkynes with 1,3-diketones

作者:Pennington Boggio Megan K; Conley Brian L; Williams Travis J*
来源:Journal of Organometallic Chemistry, 2012, 716: 6-10.
DOI:10.1016/j.jorganchem.2012.05.017

摘要

Ruthenium(III) chloride hydrate is a convenient catalyst for the addition of active methylene compounds to aryl alkynes. These reactions are rapid, operationally simple, and high yielding in cases. Most significantly, no precautions are required to exclude air or water from the reactions. All reagents are commercially available at reasonable prices, and the reactions can be conducted in disposable glassware with minimal solvent.