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摘要
Highly functionalized 1-azafluorenones were obtained from indeno[2,1-a]isoindolones through Ag2O-mediated cascade reaction. The cascade process includes the oxidation of vicinal alcohol and dihydropyridine to generate a pyridinium intermediate which is trapped in situ by a nucleophile. Functional groups such as methoxy, thiomethyl and aldehyde survived the Ag2O treatment whereas the dimethylamino group was partially demethylated.
- 出版日期2013
