Fe3O4-Mn3O4 nanocomposites with moderate magnetism for in vitro cytotoxicity studies on macrophages

作者：Rahaman Hasimur; Nath Anupam; Paul Rimi; Sengupta Mahuya; Ghosh Sujit Kumar^*

来源：RSC Advances, 2016, 6(86): 83146-83153.

DOI：10.1039/c6ra17493k

Dual magnetic iron oxide/manganese oxide nanocomposites have been synthesised by alkaline hydrolysis of a manganese precursor in the presence of preformed polyethylene glycol (PEG)-stabilised magnetite (Fe3O4) nanoparticles. The formation of the nanocomposites has been characterised by absorption spectroscopy, Fourier transform infrared spectroscopy, transmission electron microscopy, high resolution transmission electron microscopy, dynamic light scattering, selected area electron diffraction patterns, energy dispersive X-ray analysis, elemental mapping, X-ray diffraction patterns, Raman spectroscopy, thermogravimetric analysis and vibrating sample magnetometry. It has been shown that the synthesised Fe3O4-Mn3O4 nanocomposites exhibit reduced magnetism compared to the superparamagnetic Fe3O4 nanoparticles. The moderate magnetism of the Fe3O4-Mn3O4 nanocomposites offers a viable platform for in vitro cytotoxicity studies on macrophages.

• 出版日期2016