Scallop genome provides insights into evolution of bilaterian karyotype and development

作者：Wang, Shi; Zhang, Jinbo; Jiao, Wenqian; Li, Ji; Xun, Xiaogang; Sun, Yan; Guo, Ximing; Huan, Pin; Dong, Bo; Zhang, Lingling; Hu, Xiaoli; Sun, Xiaoqing; Wang, Jing; Zhao, Chengtian; Wang, Yangfan; Wang, Dawei; Huang, Xiaoting; Wang, Ruijia; Lv, Jia; Li, Yuli; Zhang, Zhifeng; Liu, Baozhong; Lu, Wei; Hui, Yuanyuan; Liang, Jun; Zhou, Zunchun; Hou, Rui; Li, Xue; Liu, Yunchao; Li, Hengde; Ning, Xianhui; Lin, Yu; Zhao, Liang; Xing, Qiang; Dou, Jinzhuang; Li, Yangping; Mao, Junxia; Guo, Haobing

来源：Nature Ecology & Evolution, 2017, 1(5): 0120.

DOI：10.1038/s41559-017-0120

• DIFFERENTIAL EXPRESSION ANALYSIS
• PLATYNEREIS-DUMERILII
• AMPHIOXUS GENOME
• GENE-EXPRESSION
• PEARL OYSTER
• HOX
• EYE
• SEQUENCE
• ALIGNMENT
• CONSTRUCTION

Reconstructing the genomes of bilaterian ancestors is central to our understanding of animal evolution, where knowledge from ancient and/or slow-evolving bilaterian lineages is critical. Here we report a high-quality, chromosome-anchored reference genome for the scallop Patinopecten yessoensis, a bivalve mollusc that has a slow-evolving genome with many ancestral features. Chromosome-based macrosynteny analysis reveals a striking correspondence between the 19 scallop chromosomes and the 17 presumed ancestral bilaterian linkage groups at a level of conservation previously unseen, suggesting that the scallop may have a karyotype close to that of the bilaterian ancestor. Scallop Hox gene expression follows a new mode of subcluster temporal co-linearity that is possibly ancestral and may provide great potential in supporting diverse bilaterian body plans. Transcriptome analysis of scallop mantle eyes finds unexpected diversity in phototransduction cascades and a potentially ancient Pax2/5/8-dependent pathway for noncephalic eyes. The outstanding preservation of ancestral karyotype and developmental control makes the scallop genome a valuable resource for understanding early bilaterian evolution and biology.

• 出版日期2017-5
• 单位中国科学院海洋研究所; 中国海洋大学; 中国水产科学研究院; 辽宁省海洋水产科学研究院