An adhesive F-19 MRI chemical probe allows signal off-to-on-type molecular sensing in a biological environment

作者：Doura Tomohiro; Hata Ryunosuke; Nonaka Hiroshi; Sugihara Fuminori; Yoshioka Yoshichika; Sando Shinsuke^*

来源：Chemical Communications, 2013, 49(97): 11421-11423.

DOI：10.1039/c3cc46471g

We report a new strategy for designing a signal off-to-on-type F-19 MRI chemical probe that operates in biological environments. The present strategy is based on the control of adherence of a F-19 MRI chemical probe to certain blood proteins, accompanied by a change in transverse relaxation time of F-19 nuclei.

• 出版日期2013