Development and validation of a Hindi language health-related quality of life questionnaire for melasma in Indian patients

作者：Sarkar Rashmi^*; Garg Shilpa; Dominguez Arturo; Balkrishnan Rajesh; Jain R K; Pandya Amit G

来源：Indian Journal of Dermatology, Venereology and Leprology, 2016, 82(1): 16-22.

DOI：10.4103/0378-6323.168937

• Hindi
• melasma
• quality of life

Background: Melasma, which is fairly common in Indians, causes significant emotional and psychological impact. A Hindi instrument would be useful to assess the impact of melasma on the quality of life in Indian patients. Objective: To create a semantic equivalent of the original MELASQOL questionnaire in Hindi and validate it. Methods: A Hindi adaptation of the original MELASQOL (Hi-MELASQOL) was prepared using previously established guidelines. After pre-testing, the Hi-MELASQOL questionnaire was administered to 100 women with melasma visiting the out-patient registration counter of Safdarjung Hospital, Delhi. These women were also administered a Hindi equivalent of the Health Related Quality of Life (HRQOL) questionnaire. Melasma area severity index (MASI) of all the participants was calculated. Results: The mean MASI score was 20.0 +/- 7.5 and Hi-MELASQOL score was 37.19 +/- 18.15; both were highly, positively and significantly correlated. Reliability analysis showed satisfactory results. Physical health, emotional well-being and social life were the most adversely affected life domains. Limitations: It was a single-center study and the number of patients studied could have been larger. Conclusion: Hi-MELASQOL is a reliable and validated tool to measure the quality of life in Indians with melasma.

• 出版日期2016-2