A 60-year-old lady with leonine facies: A rare diagnosis

作者:Mutreja Deepti*; Purohit Abhishek; Singh Pawan K; Pati H P
来源:Indian Journal of Pathology and Microbiology, 2012, 55(4): 566-568.
DOI:10.4103/0377-4929.107824

摘要

Systemic mastocytosis is a rare clonal disorder characterized by mast cell infiltration of one or more organs, with or without skin involvement. Leonine facies is a rare presentation and corresponds to the morphologic manifestation of diffuse dermal infiltration of the face as a result of long standing disease. Bone marrow aspiration and biopsy findings in a 60-year-old woman, who had extensive cutaneous infiltration due to systemic mastocytosis, resulting in 'leonine facies,' are described, and causes of leonine facies are discussed.

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