A 5 ' Leader Sequence Regulates Expression of Methanosarcinal CO Dehydrogenase/Acetyl Coenzyme A Synthase

作者:Anderson Kimberly L; Apolinario Ethel E; MacAuley Sheridan R; Sowers Kevin R*
来源:Journal of Bacteriology, 2009, 191(22): 7123-7128.
DOI:10.1128/JB.00731-09

摘要

In vivo expression of CO dehydrogenase/acetyl coenzyme A synthase in Methanosarcina spp. is coordinately regulated in response to substrate by at least two mechanisms: differential transcription initiation and early elongation termination near the 3' end of a 371-bp leader sequence. This is the first report of regulation of transcription elongation in the Archaea.

  • 出版日期2009-11-15